Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
poxBPyruvate dehydrogenase; Belongs to the TPP enzyme family. (583 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase small subunit.
 
 0.991
AMY54468.1
NAD-dependent malic enzyme.
 
 0.948
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.943
mftD_1
Putative mycofactocin system heme/flavin oxidoreductase MftD.
  
 
 0.940
lldD_1
Putative L-lactate dehydrogenase.
  
 
 0.940
AMY52959.1
Lactate 2-monooxygenase.
  
 
 0.940
lldD_2
Putative L-lactate dehydrogenase.
  
 
 0.940
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.928
cfiB_1
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.927
cfiB_2
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.927
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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