Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gabD1Succinate-semialdehyde dehydrogenase [NADP(+)] 1. (291 aa)    
Predicted Functional Partners:
sad_3
Succinate semialdehyde dehydrogenase [NAD(P)+] Sad.
     0.994
gabT_1
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.971
davT
5-aminovalerate aminotransferase DavT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.928
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
  
 0.920
garL
5-keto-4-deoxy-D-glucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.911
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.901
icd
Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family.
    
 0.887
gltA2
Citrate synthase 1; Belongs to the citrate synthase family.
  
 0.881
citA
Putative citrate synthase 2; Belongs to the citrate synthase family.
  
 0.881
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.812
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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