Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
icdIsocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (745 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase.
  
 
 0.949
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
   
 
 0.943
gltB_1
Glutamate synthase [NADPH] large chain.
     
 0.895
gltB_2
Glutamate synthase [NADPH] large chain.
     
 0.895
gabD1
Succinate-semialdehyde dehydrogenase [NADP(+)] 1.
    
 0.887
gdhA
NAD(P)-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.868
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.829
gdh
NAD-specific glutamate dehydrogenase.
   
 
 0.816
argH_1
Argininosuccinate lyase.
    
 0.812
gltD_1
Glutamate synthase [NADPH] small chain.
   
 
 0.810
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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