Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tfdFMaleylacetate reductase. (356 aa)    
Predicted Functional Partners:
npcC
Hydroxyquinol 1,2-dioxygenase.
 
 0.997
AMY53442.1
Hypothetical protein.
  
 
 0.911
clcD
Carboxymethylenebutenolidase.
  
 
 0.909
catD
3-oxoadipate enol-lactonase 2.
  
 
 0.907
AMY54706.1
Hypothetical protein.
       0.668
todS
Sensor histidine kinase TodS.
  
  
 0.573
adhC2
NADP-dependent alcohol dehydrogenase C 2.
  
 
 0.495
adhT_1
Alcohol dehydrogenase.
  
 
 0.485
adhT_2
Alcohol dehydrogenase.
  
 
 0.462
fruA
PTS system fructose-specific EIIABC component.
  
  
 0.446
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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