Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfdE_2Acetyl-CoA:oxalate CoA-transferase; Belongs to the CoA-transferase III family. (390 aa)    
Predicted Functional Partners:
accD3_3
Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta.
     
 0.788
bar
Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family.
       0.559
upp_2
Uracil phosphoribosyltransferase; Belongs to the UPRTase family.
     
 0.495
aam_3
Acylamidase.
    
  0.491
yngG
Hydroxymethylglutaryl-CoA lyase YngG; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
  0.444
fabF_2
3-oxoacyl-[acyl-carrier-protein] synthase 2.
  
 0.437
aam_2
Acylamidase; Belongs to the amidase family.
    
  0.423
ilvB1
Acetolactate synthase large subunit IlvB1.
  
 
 0.419
pucR_4
Purine catabolism regulatory protein.
 
     0.411
poxB
Pyruvate dehydrogenase; Belongs to the TPP enzyme family.
  
 
 0.400
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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