Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
ureCUrease subunit alpha. (573 aa)    
Predicted Functional Partners:
ureA
Urease subunit alpha; Belongs to the urease beta subunit family.
 0.999
ureF
Urease accessory protein UreF.
 
 
 0.989
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.974
ureD
Urease accessory protein UreD.
 
 
 0.951
kipA_1
KipI antagonist.
    
 0.917
alc
Allantoicase; Belongs to the allantoicase family.
    
  0.906
atzF
Allophanate hydrolase.
     
  0.900
AMY55506.1
Putative esterase.
       0.658
AMY55507.1
Hypothetical protein; Belongs to the HpcH/HpaI aldolase family.
       0.624
amiC_2
Aliphatic amidase expression-regulating protein.
 
   
 0.573
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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