Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tldDMetalloprotease TldD. (508 aa)    
Predicted Functional Partners:
AMY55545.1
Hypothetical protein.
 
     0.971
AMY55543.1
Hypothetical protein.
       0.871
desK_6
Sensor histidine kinase DesK.
       0.769
egtB
Iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
     
 0.636
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.631
lpdA
NAD(P)H dehydrogenase (quinone).
   
  
 0.627
end
Putative endonuclease 4.
      
 0.625
cobM
Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
      
 0.625
liaR_2
Transcriptional regulatory protein LiaR.
     
 0.602
AMY55540.1
Hypothetical protein.
  
    0.500
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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