| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMY51902.1 | pup | A3L23_00543 | A3L23_04261 | Hypothetical protein. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.424 |
| AMY53410.1 | AMY53659.1 | A3L23_02065 | A3L23_02318 | Hypothetical protein. | Hypothetical protein. | 0.477 |
| AMY53410.1 | arc | A3L23_02065 | A3L23_04263 | Hypothetical protein. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.844 |
| AMY53410.1 | dop | A3L23_02065 | A3L23_04262 | Hypothetical protein. | Pup deamidase/depupylase. | 0.656 |
| AMY53410.1 | pafA | A3L23_02065 | A3L23_04257 | Hypothetical protein. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.723 |
| AMY53410.1 | prcA2 | A3L23_02065 | A3L23_04259 | Hypothetical protein. | Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.981 |
| AMY53410.1 | prcB1 | A3L23_02065 | A3L23_04260 | Hypothetical protein. | Proteasome subunit beta 1; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.940 |
| AMY53410.1 | pup | A3L23_02065 | A3L23_04261 | Hypothetical protein. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.635 |
| AMY53659.1 | AMY53410.1 | A3L23_02318 | A3L23_02065 | Hypothetical protein. | Hypothetical protein. | 0.477 |
| AMY53659.1 | AMY55254.1 | A3L23_02318 | A3L23_03941 | Hypothetical protein. | Hypothetical protein. | 0.439 |
| AMY53659.1 | prcA2 | A3L23_02318 | A3L23_04259 | Hypothetical protein. | Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.463 |
| AMY53659.1 | pup | A3L23_02318 | A3L23_04261 | Hypothetical protein. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.522 |
| AMY55254.1 | AMY53659.1 | A3L23_03941 | A3L23_02318 | Hypothetical protein. | Hypothetical protein. | 0.439 |
| AMY55254.1 | prcA2 | A3L23_03941 | A3L23_04259 | Hypothetical protein. | Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.402 |
| AMY55254.1 | pup | A3L23_03941 | A3L23_04261 | Hypothetical protein. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.416 |
| arc | AMY53410.1 | A3L23_04263 | A3L23_02065 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Hypothetical protein. | 0.844 |
| arc | clpS | A3L23_04263 | A3L23_03577 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.468 |
| arc | dop | A3L23_04263 | A3L23_04262 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Pup deamidase/depupylase. | 0.946 |
| arc | pafA | A3L23_04263 | A3L23_04257 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.930 |
| arc | prcA2 | A3L23_04263 | A3L23_04259 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.994 |
