Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kuHypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (323 aa)    
Predicted Functional Partners:
AMY52902.1
Hypothetical protein; Multifunctional non-homologous end joining DNA repair protein LigD.
 
  
 0.975
ligC
DNA ligase C1.
 
  
 0.919
AMY52872.1
Hypothetical protein; Multifunctional non-homologous end joining protein LigD.
 
  
 0.884
AMY54041.1
Hypothetical protein; Multifunctional non-homologous end joining protein LigD.
 
  
 0.884
ligB
DNA ligase B.
 
  
 0.805
crtL
Lycopene beta cyclase.
       0.800
fabG_14
3-oxoacyl-[acyl-carrier-protein] reductase FabG.
       0.665
ybiT_1
Putative ABC transporter ATP-binding protein YbiT.
       0.500
AMY52971.1
Hypothetical protein.
 
    0.414
uvrD1
ATP-dependent DNA helicase UvrD1.
      
 0.403
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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