Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrSThreonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (688 aa)    
Predicted Functional Partners:
pheT
Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.938
AMY55731.1
AP-4-A phosphorylase.
 
   
 0.903
leuS
Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.879
AMY55729.1
Phosphatidylinositol mannoside acyltransferase.
     
 0.854
pgsA
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.854
pimA_4
GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase.
     
 0.847
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
 
 0.846
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
 
 0.845
nudC_2
NADH pyrophosphatase; Belongs to the Nudix hydrolase family.
       0.842
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.841
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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