Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (357 aa)    
Predicted Functional Partners:
hemY
Protoporphyrinogen oxidase.
 
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.992
nasF
Uroporphyrinogen-III C-methyltransferase.
    
 0.962
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.960
AMY56146.1
Hypothetical protein.
 
 
 0.956
cysG
Siroheme synthase.
  
 
 0.955
AMY52030.1
Hypothetical protein.
  
 
 0.941
cld
Chlorite dismutase.
 
  
 0.923
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.897
dorA
Dimethyl sulfoxide/trimethylamine N-oxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.880
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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