acyP protein (Rhodococcus fascians D188) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

acyP

Acylphosphatase. (91 aa)

Predicted Functional Partners:

pta

0.945

ackA

0.920

poxB

0.906

thcA

0.905

ald_1

0.905

acsA_3

0.903

acsA_4

0.903

gatA_1

0.902

aam_1

0.902

gatA_2

0.902

Your Current Organism:

Rhodococcus fascians D188

NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aam_1	acyP	A3L23_00972	A3L23_04693	Acylamidase; Belongs to the amidase family.	Acylphosphatase.	0.902
aam_1	ald_1	A3L23_00972	A3L23_01007	Acylamidase; Belongs to the amidase family.	3-succinoylsemialdehyde-pyridine dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.901
ackA	acsA_3	A3L23_02647	A3L23_01437	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Acetyl-coenzyme A synthetase.	0.939
ackA	acsA_4	A3L23_02647	A3L23_02401	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.943
ackA	acyP	A3L23_02647	A3L23_04693	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Acylphosphatase.	0.920
ackA	ald_1	A3L23_02647	A3L23_01007	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	3-succinoylsemialdehyde-pyridine dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.905
ackA	poxB	A3L23_02647	A3L23_03303	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Pyruvate dehydrogenase; Belongs to the TPP enzyme family.	0.943
ackA	pta	A3L23_02647	A3L23_02646	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.999
ackA	thcA	A3L23_02647	A3L23_00286	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	EPTC-inducible aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.905
acsA_3	ackA	A3L23_01437	A3L23_02647	Acetyl-coenzyme A synthetase.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.939
acsA_3	acsA_4	A3L23_01437	A3L23_02401	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.913
acsA_3	acyP	A3L23_01437	A3L23_04693	Acetyl-coenzyme A synthetase.	Acylphosphatase.	0.903
acsA_3	ald_1	A3L23_01437	A3L23_01007	Acetyl-coenzyme A synthetase.	3-succinoylsemialdehyde-pyridine dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.916
acsA_3	poxB	A3L23_01437	A3L23_03303	Acetyl-coenzyme A synthetase.	Pyruvate dehydrogenase; Belongs to the TPP enzyme family.	0.906
acsA_3	pta	A3L23_01437	A3L23_02646	Acetyl-coenzyme A synthetase.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.931
acsA_3	thcA	A3L23_01437	A3L23_00286	Acetyl-coenzyme A synthetase.	EPTC-inducible aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.916
acsA_4	ackA	A3L23_02401	A3L23_02647	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.943
acsA_4	acsA_3	A3L23_02401	A3L23_01437	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	Acetyl-coenzyme A synthetase.	0.913
acsA_4	acyP	A3L23_02401	A3L23_04693	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	Acylphosphatase.	0.903
acsA_4	ald_1	A3L23_02401	A3L23_01007	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	3-succinoylsemialdehyde-pyridine dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.914