Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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fpg1Formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (288 aa)    
Predicted Functional Partners:
fpg2
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
  
  
0.928
mutM
Formamidopyrimidine-DNA glycosylase.
  
  
 
0.926
rnc
Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.886
AMY56002.1
Hypothetical protein.
     
 0.865
nei1_1
Endonuclease 8 1.
  
   
 0.769
AMY56003.1
Cell wall synthesis protein Wag31.
     
 0.744
rpmF_2
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
     
 0.741
acyP
Acylphosphatase.
  
    0.725
AMY55998.1
Hypothetical protein.
       0.720
AMY55997.1
Hypothetical protein.
       0.677
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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