KFL_001070160 protein (Klebsormidium nitens)

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

KFL_001070160

Uncharacterized protein. (872 aa)

Predicted Functional Partners:

KFL_000160540

0.704

KFL_001270040

0.704

KFL_008420050

0.704

KFL_000570210

0.693

KFL_002880080

0.693

KFL_002080120

0.693

KFL_001480080

0.693

KFL_007060020

0.693

KFL_008460020

0.693

KFL_003260040

0.689

Your Current Organism:

Klebsormidium nitens

NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KFL_000160540	KFL_000570210	A0A1Y1HL11	A0A0U9HIS8	Phosphoglucomutase.	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	0.675
KFL_000160540	KFL_001070160	A0A1Y1HL11	A0A1Y1HUK1	Phosphoglucomutase.	Uncharacterized protein.	0.704
KFL_000160540	KFL_001480080	A0A1Y1HL11	A0A1Y1I1X2	Phosphoglucomutase.	Glucose-1-phosphate adenylyltransferase; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.871
KFL_000160540	KFL_002080120	A0A1Y1HL11	A0A1Y1I1P3	Phosphoglucomutase.	Glucose-1-phosphate adenylyltransferase; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.835
KFL_000160540	KFL_002880080	A0A1Y1HL11	A0A0U9HP82	Phosphoglucomutase.	Nucleotidyltransferases.	0.675
KFL_000160540	KFL_007060020	A0A1Y1HL11	A0A1Y1IJ89	Phosphoglucomutase.	GDP-mannose pyrophosphorylase.	0.675
KFL_000160540	KFL_008420050	A0A1Y1HL11	A0A1Y1ILK5	Phosphoglucomutase.	Phosphoglucomutase.	0.802
KFL_000160540	KFL_008460020	A0A1Y1HL11	A0A1Y1IM91	Phosphoglucomutase.	Glucose-1-phosphate adenylyltransferase family protein.	0.679
KFL_000570210	KFL_000160540	A0A0U9HIS8	A0A1Y1HL11	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	Phosphoglucomutase.	0.675
KFL_000570210	KFL_001070160	A0A0U9HIS8	A0A1Y1HUK1	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	Uncharacterized protein.	0.693
KFL_000570210	KFL_001270040	A0A0U9HIS8	A0A1Y1I120	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	Uncharacterized protein.	0.675
KFL_000570210	KFL_002880080	A0A0U9HIS8	A0A0U9HP82	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	Nucleotidyltransferases.	0.999
KFL_000570210	KFL_008420050	A0A0U9HIS8	A0A1Y1ILK5	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	Phosphoglucomutase.	0.675
KFL_001070160	KFL_000160540	A0A1Y1HUK1	A0A1Y1HL11	Uncharacterized protein.	Phosphoglucomutase.	0.704
KFL_001070160	KFL_000570210	A0A1Y1HUK1	A0A0U9HIS8	Uncharacterized protein.	Eukaryotic translation initiation factor eIF-2B epsilon subunit.	0.693
KFL_001070160	KFL_001270040	A0A1Y1HUK1	A0A1Y1I120	Uncharacterized protein.	Uncharacterized protein.	0.704
KFL_001070160	KFL_001480080	A0A1Y1HUK1	A0A1Y1I1X2	Uncharacterized protein.	Glucose-1-phosphate adenylyltransferase; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.693
KFL_001070160	KFL_002080120	A0A1Y1HUK1	A0A1Y1I1P3	Uncharacterized protein.	Glucose-1-phosphate adenylyltransferase; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.693
KFL_001070160	KFL_002880080	A0A1Y1HUK1	A0A0U9HP82	Uncharacterized protein.	Nucleotidyltransferases.	0.693
KFL_001070160	KFL_003260040	A0A1Y1HUK1	A0A1Y1ID38	Uncharacterized protein.	Uncharacterized protein.	0.689

page 1 of 4

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

3 of 4

2.43

1.93

0.00054

GO:0006281

DNA repair

4 of 50

1.46

1.23

0.0020

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003690

Double-stranded DNA binding

3 of 14

1.89

1.25

0.0057

GO:0003678

DNA helicase activity

3 of 14

1.89

1.25

0.0057

GO:0004527

Exonuclease activity

3 of 20

1.73

1.2

0.0057

GO:0016887

ATP hydrolysis activity

3 of 41

1.42

0.86

0.0179

GO:0008408

3-5 exonuclease activity

2 of 9

1.9

0.86

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033202

DNA helicase complex

3 of 8

2.13

2.0

0.00027

GO:1902494

Catalytic complex

4 of 68

1.33

1.21

0.00092

GO:0032991

Protein-containing complex

5 of 170

1.03

0.88

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1230

PD-(D/E)XK nuclease superfamily, and CBS domain

4 of 6

2.38

3.11

3.40e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033202

DNA helicase complex

3 of 13

1.92

1.48

0.0020

GOCC:0044815

DNA packaging complex

3 of 15

1.86

1.46

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 11

1.99

1.9

0.00033

KW-0234

DNA repair

4 of 31

1.67

1.72

0.00024

KW-0227

DNA damage

4 of 31

1.67

1.72

0.00024

KW-0347

Helicase

3 of 20

1.73

1.5

0.0012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13361

UvrD-like helicase C-terminal domain

3 of 3

2.56

2.31

0.00013

PF12705

PD-(D/E)XK nuclease superfamily

3 of 4

2.43

2.28

0.00013

PF13245

AAA domain

2 of 5

2.16

0.99

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038726

PD-(D/E)XK endonuclease-like domain, AddAB-type

3 of 4

2.43

1.92

0.00058

IPR011604

PD-(D/E)XK endonuclease-like domain superfamily

3 of 4

2.43

1.92

0.00058

IPR011335

Restriction endonuclease type II-like

3 of 7

2.19

1.82

0.00067

IPR014016

UvrD-like helicase, ATP-binding domain

3 of 8

2.13

1.8

0.00068

IPR000212

DNA helicase, UvrD/REP type

3 of 8

2.13

1.8

0.00068

(more ...)

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