STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_000830240Autophagy_act_C domain-containing protein. (228 aa)    
Predicted Functional Partners:
KFL_006980070
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Belongs to the ATG12 family.
    
 0.962
KFL_004660030
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
   
 0.932
KFL_002810120
Autophagy protein 5; Required for autophagy.
    
 0.849
KFL_003240190
Autophagy-related protein.
   
 0.681
KFL_001250120
NEDD8-activating complex catalytic component UBA3.
   
 0.677
KFL_006150010
Uncharacterized protein.
      
 0.667
KFL_000080090
Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family.
   
 0.666
KFL_000710250
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
 0.666
KFL_000940140
SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.
   
 0.666
KFL_002770010
Rhodanese domain-containing protein.
   
 0.666
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
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