node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KFL_000080090 | KFL_000710250 | A0A1Y1HI12 | A0A1Y1HR69 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.400 |
KFL_000080090 | KFL_000830240 | A0A1Y1HI12 | A0A1Y1HUN8 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Autophagy_act_C domain-containing protein. | 0.666 |
KFL_000080090 | KFL_001250120 | A0A1Y1HI12 | A0A1Y1I240 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | NEDD8-activating complex catalytic component UBA3. | 0.804 |
KFL_000080090 | KFL_002810120 | A0A1Y1HI12 | A0A1Y1I5R9 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Autophagy protein 5; Required for autophagy. | 0.749 |
KFL_000080090 | KFL_003240190 | A0A1Y1HI12 | A0A1Y1IFW0 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Autophagy-related protein. | 0.852 |
KFL_000080090 | KFL_004660030 | A0A1Y1HI12 | A0A1Y1IIG1 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.792 |
KFL_000080090 | KFL_006150010 | A0A1Y1HI12 | A0A1Y1IL99 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Uncharacterized protein. | 0.687 |
KFL_000080090 | KFL_006980070 | A0A1Y1HI12 | A0A1Y1IJA8 | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Belongs to the ATG12 family. | 0.826 |
KFL_000710250 | KFL_000080090 | A0A1Y1HR69 | A0A1Y1HI12 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | 0.400 |
KFL_000710250 | KFL_000830240 | A0A1Y1HR69 | A0A1Y1HUN8 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Autophagy_act_C domain-containing protein. | 0.666 |
KFL_000710250 | KFL_000940140 | A0A1Y1HR69 | A0A1Y1HTF5 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.440 |
KFL_000710250 | KFL_001250120 | A0A1Y1HR69 | A0A1Y1I240 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | NEDD8-activating complex catalytic component UBA3. | 0.999 |
KFL_000710250 | KFL_002810120 | A0A1Y1HR69 | A0A1Y1I5R9 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Autophagy protein 5; Required for autophagy. | 0.681 |
KFL_000710250 | KFL_003240190 | A0A1Y1HR69 | A0A1Y1IFW0 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Autophagy-related protein. | 0.864 |
KFL_000710250 | KFL_004660030 | A0A1Y1HR69 | A0A1Y1IIG1 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.429 |
KFL_000710250 | KFL_006150010 | A0A1Y1HR69 | A0A1Y1IL99 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Uncharacterized protein. | 0.586 |
KFL_000710250 | KFL_006980070 | A0A1Y1HR69 | A0A1Y1IJA8 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Belongs to the ATG12 family. | 0.833 |
KFL_000830240 | KFL_000080090 | A0A1Y1HUN8 | A0A1Y1HI12 | Autophagy_act_C domain-containing protein. | Ubiquitin activating enzyme UBA1; Belongs to the ubiquitin-activating E1 family. | 0.666 |
KFL_000830240 | KFL_000710250 | A0A1Y1HUN8 | A0A1Y1HR69 | Autophagy_act_C domain-containing protein. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.666 |
KFL_000830240 | KFL_000940140 | A0A1Y1HUN8 | A0A1Y1HTF5 | Autophagy_act_C domain-containing protein. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.666 |