STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_001250020Chromodomain-helicase DNA-binding protein. (1903 aa)    
Predicted Functional Partners:
KFL_011820010
HMG (High mobility group) box protein.
    
 0.836
KFL_003940030
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.816
KFL_001450210
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.806
KFL_003190150
Non-catalytic subunit of nuclear DNA-dependent RNA polymerases.
   
 0.795
KFL_002100090
Uncharacterized protein.
   
 
 0.786
KFL_005900040
Putative SNF2 family N-terminal domain containing protein.
  
0.784
KFL_000400260
Uncharacterized protein.
    
 0.782
KFL_003390100
Global transcription factor.
    
 
 0.736
KFL_004930070
DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
   
 0.736
KFL_000810310
Eukaryotic translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.728
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.