node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | KFL_000070060 | A0A1Y1HUF1 | A0A1Y1HHV0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA recombinational repair protein BRCA2. | 0.683 |
FEN1 | KFL_000750280 | A0A1Y1HUF1 | A0A0U9HJ04 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | WD40 protein. | 0.748 |
FEN1 | KFL_001460120 | A0A1Y1HUF1 | A0A1Y1I3Q9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Transglutaminase-like. | 0.676 |
FEN1 | KFL_003200020 | A0A1Y1HUF1 | A0A1Y1I7I2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.653 |
FEN1 | KFL_004050070 | A0A1Y1HUF1 | A0A1Y1IDX4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Macro domain-containing protein. | 0.641 |
FEN1 | KFL_004560170 | A0A1Y1HUF1 | A0A1Y1IJ66 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ER-Golgi vesicle-tethering protein/Myosin class II heavy chain. | 0.717 |
FEN1 | KFL_005450070 | A0A1Y1HUF1 | A0A1Y1IM09 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RPA_C domain-containing protein. | 0.717 |
FEN1 | KFL_007640030 | A0A1Y1HUF1 | A0A1Y1IRE5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly (ADP-ribose) glycohydrolase. | 0.617 |
KFL_000070060 | FEN1 | A0A1Y1HHV0 | A0A1Y1HUF1 | DNA recombinational repair protein BRCA2. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.683 |
KFL_000070060 | KFL_000610170 | A0A1Y1HHV0 | A0A0U9HKJ8 | DNA recombinational repair protein BRCA2. | Putative DNA repair protein XPGC. | 0.683 |
KFL_000070060 | KFL_003200020 | A0A1Y1HHV0 | A0A1Y1I7I2 | DNA recombinational repair protein BRCA2. | Uncharacterized protein. | 0.658 |
KFL_000070060 | KFL_004560170 | A0A1Y1HHV0 | A0A1Y1IJ66 | DNA recombinational repair protein BRCA2. | ER-Golgi vesicle-tethering protein/Myosin class II heavy chain. | 0.646 |
KFL_000070060 | KFL_005450070 | A0A1Y1HHV0 | A0A1Y1IM09 | DNA recombinational repair protein BRCA2. | RPA_C domain-containing protein. | 0.646 |
KFL_000070060 | KFL_009620020 | A0A1Y1HHV0 | A0A1Y1ISM1 | DNA recombinational repair protein BRCA2. | DNA repair protein XPGC. | 0.683 |
KFL_000610170 | KFL_000070060 | A0A0U9HKJ8 | A0A1Y1HHV0 | Putative DNA repair protein XPGC. | DNA recombinational repair protein BRCA2. | 0.683 |
KFL_000610170 | KFL_000750280 | A0A0U9HKJ8 | A0A0U9HJ04 | Putative DNA repair protein XPGC. | WD40 protein. | 0.672 |
KFL_000610170 | KFL_001460120 | A0A0U9HKJ8 | A0A1Y1I3Q9 | Putative DNA repair protein XPGC. | Transglutaminase-like. | 0.676 |
KFL_000610170 | KFL_003200020 | A0A0U9HKJ8 | A0A1Y1I7I2 | Putative DNA repair protein XPGC. | Uncharacterized protein. | 0.653 |
KFL_000610170 | KFL_004050070 | A0A0U9HKJ8 | A0A1Y1IDX4 | Putative DNA repair protein XPGC. | Macro domain-containing protein. | 0.641 |
KFL_000610170 | KFL_004560170 | A0A0U9HKJ8 | A0A1Y1IJ66 | Putative DNA repair protein XPGC. | ER-Golgi vesicle-tethering protein/Myosin class II heavy chain. | 0.717 |