STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_002720020Apyrase; Belongs to the GDA1/CD39 NTPase family. (460 aa)    
Predicted Functional Partners:
KFL_001330130
Nucleoside phosphatase family protein; Belongs to the GDA1/CD39 NTPase family.
  
 
0.940
KFL_009510020
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
  
 
0.917
PURA
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.894
KFL_001860220
Phosphodiesterase/nucleotide pyrophosphatase.
   
 0.888
KFL_001250130
GMP synthase.
   
 
 0.887
KFL_000370030
Nucleoside-triphosphatase THEP1.
     
 0.885
KFL_003730020
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.875
KFL_000790120
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
   
 
  0.871
KFL_003200160
Adenylate kinase; Belongs to the adenylate kinase family.
   
 
 0.871
KFL_003740030
Adenylate kinase; Belongs to the adenylate kinase family.
   
 
 0.871
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
Server load: low (20%) [HD]