STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_004800010Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (567 aa)    
Predicted Functional Partners:
KFL_003810040
Helicase conserved C-terminal domain containing protein.
    
 0.995
KFL_000320320
Aspartyl/Asparaginyl-tRNA synthetase class IIb.
   
 0.906
KFL_000040300
Aspartyl/Asparaginyl-tRNA synthetase class IIb.
   
 0.906
KFL_002150120
Aspartyl/Asparaginyl-tRNA synthetase class IIb.
   
 0.906
KFL_002790130
Putative endonuclease containing ERCC4 domain.
   
 0.894
KFL_000570470
DUF1767 domain-containing protein.
    
 0.893
KFL_000880040
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
    
 
 0.891
KFL_002370080
Uncharacterized protein.
    
 
 0.891
KFL_000340330
Endonuclease.
   
 0.859
KFL_000860370
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.858
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
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