STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_006060090Transcription elongation factor SPT4 homolog; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex; Belongs to the SPT4 family. (121 aa)    
Predicted Functional Partners:
KFL_003190150
Non-catalytic subunit of nuclear DNA-dependent RNA polymerases.
   
 0.996
KFL_000610160
DNA-directed RNA polymerase II subunit 4.
   
 0.994
KFL_004750100
DNA-directed RNA polymerase II subunit 11.
   
 0.993
KFL_000530260
Uncharacterized protein.
   
 0.992
KFL_000170490
DNA-directed RNA polymerase subunit K.
   
 0.989
KFL_002610100
DNA-directed RNA polymerase II subunit 8; Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
   
 0.986
KFL_003390100
Global transcription factor.
    
 0.983
KFL_004850090
DNA-directed RNA polymerase II subunit 10.
   
 0.982
KFL_001450210
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.979
KFL_000040070
ARC6 homolog.
   
 0.977
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
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