KFL_009240040 protein (Klebsormidium nitens)

Nodes:

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Coexpression

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[Homology]

Score

KFL_009240040

Ribonuclease III. (337 aa)

Predicted Functional Partners:

KFL_004950030

0.697

KFL_000080510

0.686

KFL_000010480

0.680

KFL_000640170

0.680

KFL_000850250

0.680

KFL_002720160

0.680

KFL_004520030

0.680

KFL_004800020

0.680

KFL_001360250

0.666

KFL_003310010

0.661

Your Current Organism:

Klebsormidium nitens

NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KFL_000010480	KFL_009240040	A0A0U9HJK8	A0A1Y1IN72	Argonaute family protein; Belongs to the argonaute family.	Ribonuclease III.	0.680
KFL_000080510	KFL_001360250	A0A1Y1HI50	A0A1Y1I4T1	Ribosomal protein S6 family protein.	Pentatricopeptide repeat domain containing protein.	0.999
KFL_000080510	KFL_003310010	A0A1Y1HI50	A0A1Y1ICD0	Ribosomal protein S6 family protein.	Mitochondrial ribosomal protein L23.	0.983
KFL_000080510	KFL_004950030	A0A1Y1HI50	A0A1Y1IDZ7	Ribosomal protein S6 family protein.	Uncharacterized protein.	0.981
KFL_000080510	KFL_009240040	A0A1Y1HI50	A0A1Y1IN72	Ribosomal protein S6 family protein.	Ribonuclease III.	0.686
KFL_000640170	KFL_009240040	A0A1Y1HQF1	A0A1Y1IN72	Uncharacterized protein.	Ribonuclease III.	0.680
KFL_000850250	KFL_009240040	A0A1Y1HWP2	A0A1Y1IN72	Argonaute family protein; Belongs to the argonaute family.	Ribonuclease III.	0.680
KFL_001360250	KFL_000080510	A0A1Y1I4T1	A0A1Y1HI50	Pentatricopeptide repeat domain containing protein.	Ribosomal protein S6 family protein.	0.999
KFL_001360250	KFL_003310010	A0A1Y1I4T1	A0A1Y1ICD0	Pentatricopeptide repeat domain containing protein.	Mitochondrial ribosomal protein L23.	0.972
KFL_001360250	KFL_004950030	A0A1Y1I4T1	A0A1Y1IDZ7	Pentatricopeptide repeat domain containing protein.	Uncharacterized protein.	0.981
KFL_001360250	KFL_009240040	A0A1Y1I4T1	A0A1Y1IN72	Pentatricopeptide repeat domain containing protein.	Ribonuclease III.	0.666
KFL_002720160	KFL_009240040	A0A1Y1I866	A0A1Y1IN72	Argonaute family protein.	Ribonuclease III.	0.680
KFL_003310010	KFL_000080510	A0A1Y1ICD0	A0A1Y1HI50	Mitochondrial ribosomal protein L23.	Ribosomal protein S6 family protein.	0.983
KFL_003310010	KFL_001360250	A0A1Y1ICD0	A0A1Y1I4T1	Mitochondrial ribosomal protein L23.	Pentatricopeptide repeat domain containing protein.	0.972
KFL_003310010	KFL_004950030	A0A1Y1ICD0	A0A1Y1IDZ7	Mitochondrial ribosomal protein L23.	Uncharacterized protein.	0.987
KFL_003310010	KFL_009240040	A0A1Y1ICD0	A0A1Y1IN72	Mitochondrial ribosomal protein L23.	Ribonuclease III.	0.661
KFL_004520030	KFL_009240040	A0A1Y1IJ02	A0A1Y1IN72	Argonaute family protein; Belongs to the argonaute family.	Ribonuclease III.	0.680
KFL_004800020	KFL_009240040	A0A1Y1IK35	A0A1Y1IN72	Argonaute family protein; Belongs to the argonaute family.	Ribonuclease III.	0.680
KFL_004950030	KFL_000080510	A0A1Y1IDZ7	A0A1Y1HI50	Uncharacterized protein.	Ribosomal protein S6 family protein.	0.981
KFL_004950030	KFL_001360250	A0A1Y1IDZ7	A0A1Y1I4T1	Uncharacterized protein.	Pentatricopeptide repeat domain containing protein.	0.981

page 1 of 2

Network Stats

number of nodes:

6

number of edges:

9

average node degree:

3

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.0777

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006635

Fatty acid beta-oxidation

3 of 10

2.17

1.46

0.0017

GO:0006631

Fatty acid metabolic process

4 of 42

1.68

1.3

0.0017

GO:0006629

Lipid metabolic process

5 of 172

1.16

0.94

0.0018

GO:0006412

Translation

4 of 105

1.28

0.92

0.0048

GO:0044238

Primary metabolic process

10 of 1831

0.43

0.33

0.0097

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

4 of 55

1.56

1.17

0.0026

GO:0070403

NAD+ binding

2 of 3

2.52

1.14

0.0084

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

4 of 61

1.51

1.34

0.00069

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3915

Lipid oxidation, and 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

4 of 13

2.19

2.34

2.54e-05

CL:2855

Ribosome

4 of 33

1.78

0.00014

CL:4722

Oxidoreductase FAD-binding domain, and Response to nitrosative stress

2 of 6

2.22

1.15

0.0070

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rsi00360

Phenylalanine metabolism

5 of 15

2.22

3.73

1.96e-08

rsi00650

Butanoate metabolism

3 of 20

1.87

1.7

0.00030

rsi00362

Benzoate degradation

3 of 22

1.83

1.67

0.00031

rsi03010

Ribosome

4 of 54

1.57

1.61

0.00013

rsi00903

Limonene and pinene degradation

2 of 4

2.4

1.61

0.0010

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0036125

Fatty acid beta-oxidation multienzyme complex

3 of 6

2.4

2.02

0.00016

GOCC:0005840

Ribosome

4 of 37

1.73

1.72

0.00016

GOCC:0062077

phenylacetyl-CoA 1,2-epoxidase complex

2 of 3

2.52

1.34

0.0034

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

2.15

1.11

0.0082

GOCC:0032991

Protein-containing complex

7 of 574

0.78

0.59

0.0034

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

4 of 64

1.49

1.22

0.0014

KW-0001

2Fe-2S

2 of 8

2.1

1.04

0.0111

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF16113

Enoyl-CoA hydratase/isomerase

3 of 8

2.27

1.67

0.00069

PF02737

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain

2 of 3

2.52

1.04

0.0129

PF00970

Oxidoreductase FAD-binding domain

2 of 3

2.52

1.04

0.0129

PF00725

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

2 of 3

2.52

1.04

0.0129

PF00175

Oxidoreductase NAD-binding domain

2 of 3

2.52

1.04

0.0129

(more ...)

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