KFL_006820090 protein (Klebsormidium nitens)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

KFL_006820090

Sulfhydryl oxidase. (537 aa)

Predicted Functional Partners:

KFL_001340250

0.757

KFL_001340060

0.491

LSM1

0.478

KFL_004160110

0.437

KFL_000530420

0.431

KFL_001200050

0.431

KFL_001940090

0.412

Your Current Organism:

Klebsormidium nitens

NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KFL_000530420	KFL_001340060	A0A1Y1HV53	A0A1Y1HZ86	C2H2-type domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.698
KFL_000530420	KFL_001340250	A0A1Y1HV53	A0A1Y1HWN9	C2H2-type domain-containing protein.	Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation.	0.964
KFL_000530420	KFL_004160110	A0A1Y1HV53	A0A1Y1IJJ1	C2H2-type domain-containing protein.	Heat shock protein 90.	0.838
KFL_000530420	KFL_006820090	A0A1Y1HV53	A0A1Y1INM9	C2H2-type domain-containing protein.	Sulfhydryl oxidase.	0.431
KFL_001200050	KFL_001340060	A0A1Y1I0K1	A0A1Y1HZ86	Protein disulfide-isomerase.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.698
KFL_001200050	KFL_001340250	A0A1Y1I0K1	A0A1Y1HWN9	Protein disulfide-isomerase.	Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation.	0.975
KFL_001200050	KFL_004160110	A0A1Y1I0K1	A0A1Y1IJJ1	Protein disulfide-isomerase.	Heat shock protein 90.	0.838
KFL_001200050	KFL_006820090	A0A1Y1I0K1	A0A1Y1INM9	Protein disulfide-isomerase.	Sulfhydryl oxidase.	0.431
KFL_001340060	KFL_000530420	A0A1Y1HZ86	A0A1Y1HV53	Uncharacterized protein; Belongs to the peptidase C1 family.	C2H2-type domain-containing protein.	0.698
KFL_001340060	KFL_001200050	A0A1Y1HZ86	A0A1Y1I0K1	Uncharacterized protein; Belongs to the peptidase C1 family.	Protein disulfide-isomerase.	0.698
KFL_001340060	KFL_006820090	A0A1Y1HZ86	A0A1Y1INM9	Uncharacterized protein; Belongs to the peptidase C1 family.	Sulfhydryl oxidase.	0.491
KFL_001340250	KFL_000530420	A0A1Y1HWN9	A0A1Y1HV53	Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation.	C2H2-type domain-containing protein.	0.964
KFL_001340250	KFL_001200050	A0A1Y1HWN9	A0A1Y1I0K1	Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation.	Protein disulfide-isomerase.	0.975
KFL_001340250	KFL_006820090	A0A1Y1HWN9	A0A1Y1INM9	Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation.	Sulfhydryl oxidase.	0.757
KFL_001940090	KFL_006820090	A0A1Y1I3M4	A0A1Y1INM9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Belongs to the kynureninase family.	Sulfhydryl oxidase.	0.412
KFL_004160110	KFL_000530420	A0A1Y1IJJ1	A0A1Y1HV53	Heat shock protein 90.	C2H2-type domain-containing protein.	0.838
KFL_004160110	KFL_001200050	A0A1Y1IJJ1	A0A1Y1I0K1	Heat shock protein 90.	Protein disulfide-isomerase.	0.838
KFL_004160110	KFL_006820090	A0A1Y1IJJ1	A0A1Y1INM9	Heat shock protein 90.	Sulfhydryl oxidase.	0.437
KFL_006820090	KFL_000530420	A0A1Y1INM9	A0A1Y1HV53	Sulfhydryl oxidase.	C2H2-type domain-containing protein.	0.431
KFL_006820090	KFL_001200050	A0A1Y1INM9	A0A1Y1I0K1	Sulfhydryl oxidase.	Protein disulfide-isomerase.	0.431

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.849

expected number of edges:

23

PPI enrichment p-value:

0.00531

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042180

Cellular ketone metabolic process

4 of 68

1.94

1.89

0.00013

GO:0006744

Ubiquinone biosynthetic process

3 of 28

2.2

1.69

0.00058

GO:0044283

Small molecule biosynthetic process

6 of 324

1.44

1.52

9.52e-05

GO:0044281

Small molecule metabolic process

7 of 1034

1.0

0.88

0.00058

GO:0006568

Tryptophan metabolic process

2 of 20

2.17

0.88

0.0234

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004395

Hexaprenyldihydroxybenzoate methyltransferase activity

3 of 3

3.17

2.84

7.18e-06

GO:0008689

3-demethylubiquinone-9 3-O-methyltransferase activity

2 of 2

3.17

1.67

0.00098

GO:0008425

2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity

2 of 3

3.0

1.64

0.0011

GO:0003824

Catalytic activity

11 of 4867

0.53

0.43

0.00087

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019898

Extrinsic component of membrane

3 of 83

1.73

0.88

0.0178

GO:0031314

Extrinsic component of mitochondrial inner membrane

2 of 20

2.17

0.77

0.0373

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:16335

Ubiquinone biosynthesis, and Hexaprenyldihydroxybenzoate methyltransferase activity

3 of 11

2.61

2.04

0.00017

CL:16221

Mixed, incl. Alpha/beta hydrolase fold-3, and FAD-binding domain

4 of 77

1.89

1.79

0.00019

CL:16082

Mixed, incl. Nitrate reductase activity, and Positive regulation of exit from mitosis

2 of 6

2.69

1.32

0.0040

CL:15863

Steroid biosynthesis

2 of 23

2.11

0.8

0.0321

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00130

Ubiquinone and other terpenoid-quinone biosynthesis

3 of 50

1.95

1.69

0.00040

map01100

Metabolic pathways

11 of 2829

0.76

0.77

6.50e-07

map01110

Biosynthesis of secondary metabolites

5 of 795

0.97

0.71

0.0051

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-2142789

Ubiquinol biosynthesis

3 of 28

2.2

1.73

0.00048

MAP-8978934

Metabolism of cofactors

3 of 41

2.04

1.55

0.00093

MAP-196854

Metabolism of vitamins and cofactors

3 of 124

1.56

0.85

0.0171

MAP-1430728

Metabolism

9 of 1786

0.87

0.81

9.64e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005739

Mitochondrion

6 of 707

1.1

0.87

0.0025

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0663

Pyridoxal phosphate

2 of 24

2.09

0.81

0.0314

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01117

Cytochrome b5-like Heme/Steroid binding domain

2 of 20

2.17

0.81

0.0313

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