STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KFL_011100020Histone H2B; Belongs to the histone H2B family. (136 aa)    
Predicted Functional Partners:
KFL_003940030
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 0.998
KFL_001070200
Histone H2A; Belongs to the histone H2A family.
   
 0.959
KFL_001250190
Histone H2A; Belongs to the histone H2A family.
 
 0.954
KFL_001060030
Histone H2A; Belongs to the histone H2A family.
 
 0.952
KFL_005900040
Putative SNF2 family N-terminal domain containing protein.
    
 0.942
KFL_005090020
Histone H3; Belongs to the histone H3 family.
 
 
 0.935
KFL_003190150
Non-catalytic subunit of nuclear DNA-dependent RNA polymerases.
    
 0.906
KFL_011820010
HMG (High mobility group) box protein.
   
 0.905
KFL_003390100
Global transcription factor.
   
 
 0.897
KFL_000050700
Uncharacterized protein.
   
 0.890
Your Current Organism:
Klebsormidium nitens
NCBI taxonomy Id: 105231
Other names: K. nitens, Klebsormidium nitens (Meneghini) Lokhorst
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.