STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAWM_00390SET domain-containing protein SNOG_11806. (804 aa)    
Predicted Functional Partners:
AAWM_03192
Chromo domain-containing protein 2.
    
 0.851
AAWM_09519
Chromo domain-containing protein 1.
    
 0.851
AAWM_09742
Ubiquitin-60S ribosomal protein L40.
    
  0.821
AAWM_02567
Histone acetyltransferase type B subunit 2.
    
 0.813
AAWM_01614
SET domain-containing protein 3.
    
 0.802
AAWM_02751
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.766
AAWM_04904
Histone H4.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.754
AAWM_02346
Uncharacterized protein.
    
 0.751
AAWM_06443
Polyubiquitin.
    
  0.744
AAWM_01349
Ubiquitin-40S ribosomal protein S27a.
    
  0.731
Your Current Organism:
Aspergillus awamori
NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.