STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAWM_01453DNA replication checkpoint protein tel2. (984 aa)    
Predicted Functional Partners:
AAWM_11096
TEL2-interacting protein 1.
    
 0.992
AAWM_02435
Protein kinase rad3; Belongs to the PI3/PI4-kinase family.
    
 0.965
AAWM_07965
Phosphatidylinositol 3-kinase tor2; Belongs to the PI3/PI4-kinase family.
    
 0.959
AAWM_08057
Exosome complex exonuclease rrp6.
    
 0.959
AAWM_01944
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 
 0.931
AAWM_09542
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.925
AAWM_06486
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.920
AAWM_04467
DNA repair protein rad16.
   
 
 0.910
AAWM_01097
Transcription-associated protein 1; Belongs to the PI3/PI4-kinase family.
   
 
 0.822
AAWM_06889
Mating-type switching protein swi10.
    
 0.751
Your Current Organism:
Aspergillus awamori
NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.