AAWM_01849 protein (Aspergillus awamori) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

AAWM_01849

NAD_binding_9 domain-containing protein. (788 aa)

Predicted Functional Partners:

AAWM_07794

0.896

AAWM_06915

0.884

AAWM_02387

0.809

AAWM_00945

0.785

AAWM_08221

0.772

AAWM_01116

0.757

AAWM_09063

0.757

AAWM_09247

0.757

AAWM_00145

0.752

AAWM_03751

0.742

Your Current Organism:

Aspergillus awamori

NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAWM_00145	AAWM_00945	A0A401KD71	A0A401KFE2	5-formyltetrahydrofolate cyclo-ligase.	C-1-tetrahydrofolate synthase, cytoplasmic.	0.955
AAWM_00145	AAWM_01849	A0A401KD71	A0A401KHX5	5-formyltetrahydrofolate cyclo-ligase.	NAD_binding_9 domain-containing protein.	0.752
AAWM_00145	AAWM_07794	A0A401KD71	A0A401KZU2	5-formyltetrahydrofolate cyclo-ligase.	Methylenetetrahydrofolate dehydrogenase.	0.944
AAWM_00945	AAWM_00145	A0A401KFE2	A0A401KD71	C-1-tetrahydrofolate synthase, cytoplasmic.	5-formyltetrahydrofolate cyclo-ligase.	0.955
AAWM_00945	AAWM_01116	A0A401KFE2	A0A401KG53	C-1-tetrahydrofolate synthase, cytoplasmic.	Phosphoribosylformylglycinamidine synthase.	0.889
AAWM_00945	AAWM_01849	A0A401KFE2	A0A401KHX5	C-1-tetrahydrofolate synthase, cytoplasmic.	NAD_binding_9 domain-containing protein.	0.785
AAWM_00945	AAWM_02387	A0A401KFE2	A0A401KK32	C-1-tetrahydrofolate synthase, cytoplasmic.	Thymidylate synthase.	0.814
AAWM_00945	AAWM_03751	A0A401KFE2	A0A401KNP6	C-1-tetrahydrofolate synthase, cytoplasmic.	Dihydrofolate reductase.	0.806
AAWM_00945	AAWM_06915	A0A401KFE2	A0A401KXQ0	C-1-tetrahydrofolate synthase, cytoplasmic.	Probable thymidylate synthase.	0.932
AAWM_00945	AAWM_07794	A0A401KFE2	A0A401KZU2	C-1-tetrahydrofolate synthase, cytoplasmic.	Methylenetetrahydrofolate dehydrogenase.	0.958
AAWM_00945	AAWM_08221	A0A401KFE2	A0A401L151	C-1-tetrahydrofolate synthase, cytoplasmic.	25S rRNA (Cytosine-C(5))-methyltransferase nop2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.639
AAWM_00945	AAWM_09063	A0A401KFE2	A0A401L3V0	C-1-tetrahydrofolate synthase, cytoplasmic.	Multisite-specific tRNA:(Cytosine-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.517
AAWM_00945	AAWM_09247	A0A401KFE2	A0A401L4E3	C-1-tetrahydrofolate synthase, cytoplasmic.	25S rRNA (Cytosine-C(5))-methyltransferase rcm1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.468
AAWM_01116	AAWM_00945	A0A401KG53	A0A401KFE2	Phosphoribosylformylglycinamidine synthase.	C-1-tetrahydrofolate synthase, cytoplasmic.	0.889
AAWM_01116	AAWM_01849	A0A401KG53	A0A401KHX5	Phosphoribosylformylglycinamidine synthase.	NAD_binding_9 domain-containing protein.	0.757
AAWM_01116	AAWM_07794	A0A401KG53	A0A401KZU2	Phosphoribosylformylglycinamidine synthase.	Methylenetetrahydrofolate dehydrogenase.	0.748
AAWM_01849	AAWM_00145	A0A401KHX5	A0A401KD71	NAD_binding_9 domain-containing protein.	5-formyltetrahydrofolate cyclo-ligase.	0.752
AAWM_01849	AAWM_00945	A0A401KHX5	A0A401KFE2	NAD_binding_9 domain-containing protein.	C-1-tetrahydrofolate synthase, cytoplasmic.	0.785
AAWM_01849	AAWM_01116	A0A401KHX5	A0A401KG53	NAD_binding_9 domain-containing protein.	Phosphoribosylformylglycinamidine synthase.	0.757
AAWM_01849	AAWM_02387	A0A401KHX5	A0A401KK32	NAD_binding_9 domain-containing protein.	Thymidylate synthase.	0.809

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030001

Metal ion transport

6 of 44

1.63

2.28

1.10e-06

GO:0006812

Cation transport

7 of 72

1.48

2.05

8.58e-07

GO:0098662

Inorganic cation transmembrane transport

5 of 36

1.64

2.01

1.12e-05

GO:0006811

Ion transport

8 of 136

1.26

1.63

8.58e-07

GO:0055085

Transmembrane transport

8 of 276

0.96

3.14e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005388

P-type calcium transporter activity

4 of 4

2.49

3.1

1.27e-06

GO:0046873

Metal ion transmembrane transporter activity

5 of 20

1.89

2.64

1.27e-06

GO:0022853

Active ion transmembrane transporter activity

5 of 31

1.7

2.27

2.97e-06

GO:0008324

Cation transmembrane transporter activity

6 of 50

1.57

2.17

1.27e-06

GO:0022804

Active transmembrane transporter activity

7 of 79

1.44

1.96

9.33e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

10 of 1019

0.49

0.37

0.0046

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5719

Mixed, incl. Cation/H+ exchanger, and Calcium ion transport

5 of 12

2.11

3.17

2.39e-07

CL:5717

Mixed, incl. Cation/H+ exchanger, and Calcium ion transport

6 of 23

1.91

3.1

7.05e-08

CL:5721

Cation transport ATPase (P-type), and Cation/H+ exchanger

4 of 5

2.4

3.09

1.08e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

4 of 44

1.45

1.22

0.0012

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005887

Integral component of plasma membrane

6 of 34

1.74

2.66

2.21e-07

GOCC:0016021

Integral component of membrane

7 of 121

1.26

1.55

2.43e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1133

Transmembrane helix

9 of 702

0.6

0.45

0.0048

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00689

Cation transporting ATPase, C-terminus

4 of 4

2.49

2.99

2.15e-06

PF00122

E1-E2 ATPase

4 of 6

2.32

2.82

3.21e-06

PF13246

Cation transport ATPase (P-type)

3 of 3

2.49

2.17

8.81e-05

PF00999

Sodium/hydrogen exchanger family

2 of 6

2.02

0.78

0.0352

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006068

Cation-transporting P-type ATPase, C-terminal

4 of 4

2.49

2.79

5.30e-06

IPR044492

P-type ATPase, haloacid dehalogenase domain

4 of 5

2.4

2.75

5.30e-06

IPR023299

P-type ATPase, cytoplasmic domain N

4 of 6

2.32

2.72

5.30e-06

IPR023298

P-type ATPase, transmembrane domain superfamily

4 of 6

2.32

2.72

5.30e-06

IPR018303

P-type ATPase, phosphorylation site

4 of 6

2.32

2.72

5.30e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00831

Cation transporter/ATPase, N-terminus

3 of 3

2.49

2.29

5.11e-05

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