STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAWM_07167Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (983 aa)    
Predicted Functional Partners:
AAWM_09962
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.941
AAWM_10201
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
  
 0.941
AAWM_04541
Probable thioredoxin reductase ARB_06224.
  
 0.933
AAWM_02753
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.903
AAWM_06090
2-oxoglutarate dehydrogenase, mitochondrial.
  
 0.903
AAWM_06563
2-oxoglutarate dehydrogenase, mitochondrial.
  
 0.903
AAWM_00190
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.890
AAWM_00983
Pyruvate dehydrogenase complex protein X component, mitochondrial.
  
 0.890
AAWM_02752
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.890
AAWM_03883
annotation not available
  
 0.890
Your Current Organism:
Aspergillus awamori
NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509
Server load: low (20%) [HD]