STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAWM_07647D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (474 aa)    
Predicted Functional Partners:
AAWM_01781
Phosphoserine aminotransferase.
  
 0.988
AAWM_08097
2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.890
AAWM_01687
Tryptophan synthase.
  
 0.857
AAWM_05046
Tryptophan synthase.
  
 0.857
AAWM_08133
Tryptophan synthase.
  
 0.857
AAWM_02352
Uncharacterized kinase mug58.
     
 0.835
AAWM_04555
Uncharacterized kinase mug58.
     
 0.835
AAWM_03762
Probable phosphoserine phosphatase.
  
 0.761
AAWM_05267
Alanine--glyoxylate aminotransferase 1.
  
 
 0.759
AAWM_08099
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.737
Your Current Organism:
Aspergillus awamori
NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.