STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAWM_09582ATP-dependent DNA helicase mph1. (1124 aa)    
Predicted Functional Partners:
AAWM_00755
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.972
AAWM_00607
ATP-dependent DNA helicase srs2.
    
 
 0.932
AAWM_08169
RecQ-mediated genome instability protein 1.
    
 0.931
AAWM_01202
Crossover junction endonuclease mus81.
    
 0.929
AAWM_06889
Mating-type switching protein swi10.
    
 0.927
AAWM_00502
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.915
AAWM_10038
Werner syndrome ATP-dependent helicase homolog.
   
 0.913
AAWM_03387
ATP-dependent DNA helicase hus2/rqh1.
   
 0.903
AAWM_04467
DNA repair protein rad16.
    
 0.903
AAWM_06809
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.903
Your Current Organism:
Aspergillus awamori
NCBI taxonomy Id: 105351
Other names: A. awamori, ATCC 16877, Aspergillus awamorii, Aspergillus niger var. awamori, Aspergillus niger var. awamorii, CBS 557.65, ITEM 4509
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