node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAWM_00412 | AAWM_01944 | A0A401KE32 | A0A401KIN2 | Mediator of replication checkpoint protein 1. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.638 |
AAWM_00412 | AAWM_02435 | A0A401KE32 | A0A401KJF4 | Mediator of replication checkpoint protein 1. | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.940 |
AAWM_00412 | AAWM_02503 | A0A401KE32 | A0A401KJR6 | Mediator of replication checkpoint protein 1. | DNA repair protein crb2. | 0.832 |
AAWM_00412 | AAWM_05944 | A0A401KE32 | A0A401KUZ7 | Mediator of replication checkpoint protein 1. | Serine/threonine-protein kinase chk1. | 0.696 |
AAWM_00412 | AAWM_10685 | A0A401KE32 | A0A401L8J8 | Mediator of replication checkpoint protein 1. | Serine/threonine-protein kinase RAD53. | 0.930 |
AAWM_01944 | AAWM_00412 | A0A401KIN2 | A0A401KE32 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Mediator of replication checkpoint protein 1. | 0.638 |
AAWM_01944 | AAWM_02435 | A0A401KIN2 | A0A401KJF4 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.995 |
AAWM_01944 | AAWM_02503 | A0A401KIN2 | A0A401KJR6 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | DNA repair protein crb2. | 0.975 |
AAWM_01944 | AAWM_05944 | A0A401KIN2 | A0A401KUZ7 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Serine/threonine-protein kinase chk1. | 0.867 |
AAWM_01944 | AAWM_10685 | A0A401KIN2 | A0A401L8J8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Serine/threonine-protein kinase RAD53. | 0.912 |
AAWM_01944 | AAWM_10967 | A0A401KIN2 | A0A401L9B9 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Mitosis inhibitor protein kinase wee1. | 0.448 |
AAWM_02435 | AAWM_00412 | A0A401KJF4 | A0A401KE32 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Mediator of replication checkpoint protein 1. | 0.940 |
AAWM_02435 | AAWM_01944 | A0A401KJF4 | A0A401KIN2 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.995 |
AAWM_02435 | AAWM_02503 | A0A401KJF4 | A0A401KJR6 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | DNA repair protein crb2. | 0.978 |
AAWM_02435 | AAWM_03158 | A0A401KJF4 | A0A401KLV7 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | M-phase inducer phosphatase. | 0.833 |
AAWM_02435 | AAWM_05944 | A0A401KJF4 | A0A401KUZ7 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Serine/threonine-protein kinase chk1. | 0.981 |
AAWM_02435 | AAWM_05952 | A0A401KJF4 | A0A401KV61 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.677 |
AAWM_02435 | AAWM_07592 | A0A401KJF4 | A0A401L054 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Transcriptional regulator RFX1. | 0.933 |
AAWM_02435 | AAWM_10685 | A0A401KJF4 | A0A401L8J8 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Serine/threonine-protein kinase RAD53. | 0.970 |
AAWM_02435 | AAWM_10967 | A0A401KJF4 | A0A401L9B9 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | Mitosis inhibitor protein kinase wee1. | 0.718 |