STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuCPutative homoaconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (428 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 0.999
leuD-2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.998
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.998
EHL98418.1
Putative 3-isopropylmalate/3-methylmalate dehydrogenase; KEGG: rhi:NGR_c06160 7.5e-108 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97.
 0.991
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.984
EHL99694.1
Putative 3-isopropylmalate/3-methylmalate dehydrogenase; KEGG: vei:Veis_1349 5.3e-123 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97.
 0.981
EHM02225.1
KEGG: sno:Snov_1606 1.3e-133 tartrate dehydrogenase K07246; Psort location: Cytoplasmic, score: 9.97.
 0.958
EHL99864.1
KEGG: avi:Avi_9120 1.5e-166 tartrate dehydrogenase; K07246 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 0.948
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 0.920
EHM00575.1
Acetolactate synthase, small subunit; KEGG: acr:Acry_2832 2.4e-63 ilvH; acetolactate synthase 3 regulatory subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.848
Your Current Organism:
Acetobacteraceae bacterium AT5844
NCBI taxonomy Id: 1054213
Other names: A. bacterium AT-5844, Acetobacteraceae bacterium AT-5844
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