STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (718 aa)    
Predicted Functional Partners:
leuS
leucine--tRNA ligase; KEGG: gbe:GbCGDNIH1_0005 0. leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 
 0.956
EHM02306.1
UvrD/REP helicase; KEGG: gbe:GbCGDNIH1_0207 5.3e-281 DNA helicase II K03657; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.907
EHM02312.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.880
EHL96400.1
DNA ligase D; KEGG: xau:Xaut_4365 8.2e-205 ligD; ATP-dependent DNA ligase; K01971 DNA ligase (ATP); Psort location: Cytoplasmic, score: 7.50.
    
 0.860
EHL98820.1
KEGG: gbe:GbCGDNIH1_0904 4.7e-186 ATP-dependent DNA ligase K01971; Psort location: Cytoplasmic, score: 7.50.
    
 0.859
EHM00240.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
    0.838
bamD
Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.834
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
     
 0.778
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 0.758
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.747
Your Current Organism:
Acetobacteraceae bacterium AT5844
NCBI taxonomy Id: 1054213
Other names: A. bacterium AT-5844, Acetobacteraceae bacterium AT-5844
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