node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHL97452.1 | EHL98162.1 | HMPREF9946_04135 | HMPREF9946_03684 | Free methionine-(R)-sulfoxide reductase YebR; KEGG: sti:Sthe_3242 0.00065 GAF sensor signal transduction histidine kinase; Psort location: Cytoplasmic, score: 7.50. | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | 0.575 |
EHL98162.1 | EHL97452.1 | HMPREF9946_03684 | HMPREF9946_04135 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | Free methionine-(R)-sulfoxide reductase YebR; KEGG: sti:Sthe_3242 0.00065 GAF sensor signal transduction histidine kinase; Psort location: Cytoplasmic, score: 7.50. | 0.575 |
EHL98162.1 | EHL98892.1 | HMPREF9946_03684 | HMPREF9946_03415 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.911 |
EHL98162.1 | EHM00575.1 | HMPREF9946_03684 | HMPREF9946_02524 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | Acetolactate synthase, small subunit; KEGG: acr:Acry_2832 2.4e-63 ilvH; acetolactate synthase 3 regulatory subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 7.50. | 0.613 |
EHL98162.1 | EHM00891.1 | HMPREF9946_03684 | HMPREF9946_02402 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | Aspartate kinase, monofunctional class; KEGG: acr:Acry_1008 8.3e-173 aspartate kinase K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 0.610 |
EHL98162.1 | EHM02303.1 | HMPREF9946_03684 | HMPREF9946_01325 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | KEGG: acr:Acry_0219 9.3e-126 5,10-methylenetetrahydrofolate reductase; K00297 methylenetetrahydrofolate reductase (NADPH); Psort location: Cytoplasmic, score: 7.50. | 0.632 |
EHL98162.1 | EHM02631.1 | HMPREF9946_03684 | HMPREF9946_00900 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: msl:Msil_0179 1.5e-171 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.612 |
EHL98162.1 | EHM03502.1 | HMPREF9946_03684 | HMPREF9946_00037 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | KEGG: rce:RC1_1305 8.3e-157 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.596 |
EHL98162.1 | fhs | HMPREF9946_03684 | HMPREF9946_02342 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | Formate--tetrahydrofolate ligase; KEGG: rec:RHECIAT_CH0003236 7.4e-204 fhs; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50. | 0.537 |
EHL98162.1 | metG | HMPREF9946_03684 | HMPREF9946_00635 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.589 |
EHL98162.1 | metK | HMPREF9946_03684 | HMPREF9946_05078 | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.657 |
EHL98892.1 | EHL98162.1 | HMPREF9946_03415 | HMPREF9946_03684 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: rle:RL1357 7.4e-85 putative homocysteine S-methyltransferase K00547; Psort location: Cytoplasmic, score: 7.50. | 0.911 |
EHL98892.1 | EHM00575.1 | HMPREF9946_03415 | HMPREF9946_02524 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Acetolactate synthase, small subunit; KEGG: acr:Acry_2832 2.4e-63 ilvH; acetolactate synthase 3 regulatory subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 7.50. | 0.876 |
EHL98892.1 | EHM00891.1 | HMPREF9946_03415 | HMPREF9946_02402 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase, monofunctional class; KEGG: acr:Acry_1008 8.3e-173 aspartate kinase K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 0.949 |
EHL98892.1 | EHM02303.1 | HMPREF9946_03415 | HMPREF9946_01325 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: acr:Acry_0219 9.3e-126 5,10-methylenetetrahydrofolate reductase; K00297 methylenetetrahydrofolate reductase (NADPH); Psort location: Cytoplasmic, score: 7.50. | 0.998 |
EHL98892.1 | EHM02631.1 | HMPREF9946_03415 | HMPREF9946_00900 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: msl:Msil_0179 1.5e-171 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97. | 0.970 |
EHL98892.1 | EHM03502.1 | HMPREF9946_03415 | HMPREF9946_00037 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: rce:RC1_1305 8.3e-157 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.965 |
EHL98892.1 | fhs | HMPREF9946_03415 | HMPREF9946_02342 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Formate--tetrahydrofolate ligase; KEGG: rec:RHECIAT_CH0003236 7.4e-204 fhs; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50. | 0.970 |
EHL98892.1 | metG | HMPREF9946_03415 | HMPREF9946_00635 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.879 |
EHL98892.1 | metK | HMPREF9946_03415 | HMPREF9946_05078 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.970 |