STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (289 aa)    
Predicted Functional Partners:
EHL96400.1
DNA ligase D; KEGG: xau:Xaut_4365 8.2e-205 ligD; ATP-dependent DNA ligase; K01971 DNA ligase (ATP); Psort location: Cytoplasmic, score: 7.50.
 
  
 0.993
EHM01497.1
Hypothetical protein; KEGG: met:M446_5045 7.8e-129 putative DNA topoisomerase I; K03168 DNA topoisomerase I; Psort location: Cytoplasmic, score: 7.50.
 
    0.694
EHL98820.1
KEGG: gbe:GbCGDNIH1_0904 4.7e-186 ATP-dependent DNA ligase K01971; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.643
EHL99469.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.615
EHM02788.1
Hypothetical protein; KEGG: rpe:RPE_3645 1.8e-26 catalase K07217; Psort location: Cytoplasmic, score: 7.50.
  
    0.447
EHL96396.1
Regulatory protein ada; KEGG: pde:Pden_4239 2.7e-128 methylated-DNA--protein-cysteine methyltransferase; K10778 AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.434
EHL96397.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 8.16.
       0.434
EHL96398.1
KEGG: bmr:BMI_II527 5.3e-75 alkB; alkylated DNA repair protein AlkB; K03919 alkylated DNA repair protein.
       0.434
EHL96399.1
methylated-DNA--[protein]-cysteine S-methyltransferase; KEGG: acr:Acry_1368 8.5e-45 methylated-DNA--protein-cysteine methyltransferase; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.
       0.434
Your Current Organism:
Acetobacteraceae bacterium AT5844
NCBI taxonomy Id: 1054213
Other names: A. bacterium AT-5844, Acetobacteraceae bacterium AT-5844
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.