STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGI47439.1Mevalonate kinase. (326 aa)    
Predicted Functional Partners:
AGI47905.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase.
 
 0.971
AGI47440.1
Hypothetical protein.
       0.775
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.740
AGI47593.1
Putative hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
  
 0.726
AGI47441.1
Aspartate/tyrosine/aromatic aminotransferase.
   
   0.725
AGI47444.1
tRNA-dihydrouridine synthase.
     
 0.576
AGI47442.1
Hypothetical protein.
       0.514
AGI47443.1
Putative hydrolases of HD superfamily.
       0.514
AGI48339.1
Putative archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
   
 0.495
AGI47978.1
Selenocysteine-specific translation elongation factor.
 
  
 0.494
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.