STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGI47571.1Prephenate dehydratase. (189 aa)    
Predicted Functional Partners:
AGI47140.1
Prephenate dehydrogenase.
 
 0.964
hisC
Histidinol-phosphate aminotransferase.
 
 
 0.939
AGI47399.1
Chorismate mutase.
  
 
 0.928
AGI47547.1
Chorismate mutase.
  
 
 0.928
AGI47189.1
Aspartate/tyrosine/aromatic aminotransferase.
 
 
 0.924
AGI47572.1
ATPase component of ABC transporters with duplicated ATPase domains.
       0.773
aroB
Putative alternative 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.
  
  
 0.689
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.641
AGI47570.1
Hypothetical protein.
       0.636
AGI47573.1
Isocitrate/isopropylmalate dehydrogenase.
  
  
 0.612
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.