STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (300 aa)    
Predicted Functional Partners:
AGI47202.1
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
 0.999
AGI48393.1
Putative dinucleotide-utilizing enzyme.
    
 0.934
AGI47710.1
Serine O-acetyltransferase.
  
    0.744
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.718
mptD
Archaeal conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
       0.646
AGI48439.1
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
  
 0.600
AGI47680.1
Archaeal holliday junction resolvase (hjc).
       0.539
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.456
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.447
AGI47959.1
leucyl-tRNA synthetase, archaeal and cytosolic family; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.421
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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