STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGI48039.1Hypothetical protein. (63 aa)    
Predicted Functional Partners:
AGI47568.1
Thiamine biosynthesis protein ThiF, family 2.
  
 0.976
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.955
AGI47569.1
Thiamine biosynthesis protein ThiS.
     
  0.900
AGI47514.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.
  
 
 0.778
AGI48364.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 
 0.778
AGI48426.1
Hypothetical protein.
  
 
 0.763
AGI47565.1
Thiamine monophosphate synthase.
  
  
 0.752
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.752
AGI47712.1
Conserved hypothetical protein TIGR00269.
  
 
 0.704
AGI47623.1
Phosphomethylpyrimidine kinase.
  
    0.696
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.