STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGI48134.1ERCC4-like helicase. (516 aa)    
Predicted Functional Partners:
AGI47320.1
HRDC domain protein.
   
 
 0.964
AGI47186.1
Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit-related ssDNA-binding protein.
  
 
 0.930
AGI47057.1
LSU ribosomal protein L1P; Belongs to the universal ribosomal protein uL1 family.
    
 0.844
lig
DNA ligase I, ATP-dependent (dnl1); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 
 0.754
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
  0.719
AGI48133.1
Hypothetical protein.
 
     0.626
truD
Conserved hypothetical protein TIGR00094; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
     0.598
AGI48031.1
ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).
    
 
 0.553
AGI48356.1
Superfamily I DNA and RNA helicase.
    
 
 0.553
pcn
DNA polymerase sliding clamp subunit (PCNA-like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 
   0.539
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.