STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (402 aa)    
Predicted Functional Partners:
AGI48218.1
Precorrin-6x reductase.
     
 0.998
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.997
AGI48197.1
Porphobilinogen deaminase.
  
 0.997
AGI48195.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.938
gltX
glutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.918
AGI48199.1
Uroporphyrinogen-III synthase.
 
  
 0.916
AGI48198.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.895
AGI48130.1
Nitrogenase subunit NifH (ATPase); Belongs to the NifH/BchL/ChlL family.
     
 0.639
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.618
AGI48234.1
Siroheme synthase, N-terminal domain protein.
 
   
 0.500
Your Current Organism:
Thermoplasmatales archaeon BRNA1
NCBI taxonomy Id: 1054217
Other names: T. archaeon BRNA1
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