STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B5807_06368Uncharacterized protein. (182 aa)    
Predicted Functional Partners:
B5807_08068
Uncharacterized protein.
   
 0.859
B5807_06185
Uncharacterized protein.
    
 0.722
B5807_08298
CENP-T_C domain-containing protein.
    
 0.702
B5807_06352
Uncharacterized protein.
    
 0.702
B5807_11093
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.674
B5807_09024
WD_REPEATS_REGION domain-containing protein.
    
 0.666
B5807_05942
Uncharacterized protein.
    
 0.659
B5807_05198
ERCC4 domain-containing protein.
    
  0.650
B5807_10617
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
  0.615
B5807_08571
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.611
Your Current Organism:
Epicoccum nigrum
NCBI taxonomy Id: 105696
Other names: ATCC 24428 [[Phoma epicoccina]], CBS 173.73 [[Phoma epicoccina]], E. nigrum, Epicoccum nigrum Link, 2015, Epicoccum purpurascens, Epicoccum sp. SGSGf34, IMI 164070 [[Phoma epicoccina]], Phoma epicoccina
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.