Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
B5807_05685YrdC-like domain-containing protein. (527 aa)    
Predicted Functional Partners:
KAE1
tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]
  
 0.929
B5807_08119
Uncharacterized protein.
  
 0.883
B5807_08118
Peptidase_M22 domain-containing protein.
  
 0.883
B5807_03348
Protein kinase domain-containing protein.
   
  
 0.752
B5807_02270
Uncharacterized protein; Belongs to the CGI121/TPRKB family.
   
  
 0.746
B5807_03161
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
     
 0.674
TRM82
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
  
 0.662
B5807_09201
SAM_MT_TRM5_TYW2 domain-containing protein.
      
 0.641
B5807_07126
Uncharacterized protein.
  
  
 0.624
TRM8
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.608
Your Current Organism:
Epicoccum nigrum
NCBI taxonomy Id: 105696
Other names: ATCC 24428 [[Phoma epicoccina]], CBS 173.73 [[Phoma epicoccina]], E. nigrum, Epicoccum nigrum Link, 2015, Epicoccum purpurascens, Epicoccum sp. SGSGf34, IMI 164070 [[Phoma epicoccina]], Phoma epicoccina
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