node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B7P43_G07144 | COQ10A | A0A2J7Q269 | A0A2J7R717 | Uncharacterized protein. | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | 0.560 |
B7P43_G07144 | COQ4 | A0A2J7Q269 | A0A2J7QK90 | Uncharacterized protein. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.580 |
B7P43_G07144 | Coq7 | A0A2J7Q269 | A0A2J7R3I1 | Uncharacterized protein. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.841 |
B7P43_G07144 | coq2 | A0A2J7Q269 | A0A2J7PYB6 | Uncharacterized protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.865 |
B7P43_G07144 | coq8b_2 | A0A2J7Q269 | A0A2J7Q4Y2 | Uncharacterized protein. | Atypical kinase COQ8B, mitochondrial. | 0.805 |
COQ10A | B7P43_G07144 | A0A2J7R717 | A0A2J7Q269 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Uncharacterized protein. | 0.560 |
COQ10A | COQ4 | A0A2J7R717 | A0A2J7QK90 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.543 |
COQ10A | Coq7 | A0A2J7R717 | A0A2J7R3I1 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.582 |
COQ10A | Ethe1 | A0A2J7R717 | A0A2J7PGF2 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Persulfide dioxygenase ETHE1, mitochondrial. | 0.734 |
COQ10A | HAGH | A0A2J7R717 | A0A2J7QWP1 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Hydroxyacylglutathione hydrolase, mitochondrial. | 0.734 |
COQ10A | ND-ACP | A0A2J7R717 | A0A2J7QJG1 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.771 |
COQ10A | OXSM_1 | A0A2J7R717 | A0A2J7PVY9 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.812 |
COQ10A | coq2 | A0A2J7R717 | A0A2J7PYB6 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.606 |
COQ10A | coq6 | A0A2J7R717 | A0A2J7Q225 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial. | 0.560 |
COQ10A | coq8b_2 | A0A2J7R717 | A0A2J7Q4Y2 | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | Atypical kinase COQ8B, mitochondrial. | 0.853 |
COQ4 | B7P43_G07144 | A0A2J7QK90 | A0A2J7Q269 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | Uncharacterized protein. | 0.580 |
COQ4 | COQ10A | A0A2J7QK90 | A0A2J7R717 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | Coenzyme Q-binding protein COQ10-like protein A, mitochondrial. | 0.543 |
COQ4 | Coq7 | A0A2J7QK90 | A0A2J7R3I1 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.683 |
COQ4 | coq2 | A0A2J7QK90 | A0A2J7PYB6 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.568 |
COQ4 | coq6 | A0A2J7QK90 | A0A2J7Q225 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial. | 0.772 |