STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHF1_1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)    
Predicted Functional Partners:
HAT1
Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.
    
 0.999
SFH1
Chromatin structure remodeling complex protein sfh1.
    
 0.999
HAT2
Histone acetyltransferase type B subunit 2.
    
 0.999
HTZ1
Histone H2A; Belongs to the histone H2A family.
 
 
 0.993
ASF1
Histone chaperone asf1.
    
 
 0.991
EHS24_004172
Uncharacterized protein.
    
 
 0.990
HTA1_2
Histone H2A; Belongs to the histone H2A family.
 
 0.988
HTA1_1
Histone H2A; Belongs to the histone H2A family.
 
 0.988
HTB1_2
Histone H2B; Belongs to the histone H2B family.
 
 0.986
HTB1_1
Histone H2B; Belongs to the histone H2B family.
 
 0.986
Your Current Organism:
Apiotrichum porosum
NCBI taxonomy Id: 105984
Other names: A. porosum, CBS 2040, NRRL Y-17198, Trichosporon porosum, Trichosporon sp. ICMP 16990, Trichosporon sp. ICMP 16991, Trichosporon sp. SJ13S15, Trichosporon sp. SJ15S11, VKM Y-3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.