STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2E536Uncharacterized protein. (1560 aa)    
Predicted Functional Partners:
A0A1Y2D4Q8
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.931
A0A1Y2F265
RMI1_N domain-containing protein.
    
 0.876
A0A1Y2FZP0
Restriction endonuclease type II-like protein.
    
 0.865
A0A1Y2FLN2
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.860
A0A1Y2FZ48
3'-5' exonuclease domain-containing protein.
   
 0.851
A0A1Y2G399
3'-5' exonuclease domain-containing protein.
   
 0.851
A0A1Y2FVL2
ERCC4 domain-containing protein.
    
 0.841
A0A1Y2FB73
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.831
A0A1Y2DRR7
Nuclear transport factor 2.
    
 0.823
A0A1Y2DXF9
ATP-dependent DNA helicase.
   
 0.809
Your Current Organism:
Leucosporidium creatinivorum
NCBI taxonomy Id: 106004
Other names: CBS 8620, L. creatinivorum, Leucosporidiella creatinivora, Leucosporidiella creatinivora (Golubev) J.P. Samp., 2003, Leucosporidium creatinivorum (Golubev) V. de Garcia, M. A. Coelho, T. Maia, L. H. Rosa, A. M. Vaz, C. A. Rosa, J. P. Sampaio, P. Goncalves, M. R. van Broock andD. Libkind, 2015, Rhodotorula creatinivora, Rhodotorula creatinovora, VKM Y-2838
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.