node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1Y2BSI6 | A0A1Y2D5P2 | A0A1Y2BSI6 | A0A1Y2D5P2 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | AAA domain-containing protein. | 0.999 |
A0A1Y2BSI6 | A0A1Y2DEH9 | A0A1Y2BSI6 | A0A1Y2DEH9 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.997 |
A0A1Y2BSI6 | A0A1Y2ENK7 | A0A1Y2BSI6 | A0A1Y2ENK7 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Zf-primase domain-containing protein. | 0.942 |
A0A1Y2BSI6 | A0A1Y2ESE9 | A0A1Y2BSI6 | A0A1Y2ESE9 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | CDC45 family. | 0.983 |
A0A1Y2BSI6 | A0A1Y2EV80 | A0A1Y2BSI6 | A0A1Y2EV80 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.998 |
A0A1Y2BSI6 | A0A1Y2EZ18 | A0A1Y2BSI6 | A0A1Y2EZ18 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.997 |
A0A1Y2BSI6 | A0A1Y2FQ93 | A0A1Y2BSI6 | A0A1Y2FQ93 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Origin recognition complex subunit 2-domain-containing protein. | 0.999 |
A0A1Y2BSI6 | A0A1Y2G134 | A0A1Y2BSI6 | A0A1Y2G134 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.996 |
A0A1Y2BSI6 | A0A1Y2G5E8 | A0A1Y2BSI6 | A0A1Y2G5E8 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.997 |
A0A1Y2BSI6 | MCM7 | A0A1Y2BSI6 | A0A1Y2ELY3 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.997 |
A0A1Y2D5P2 | A0A1Y2BSI6 | A0A1Y2D5P2 | A0A1Y2BSI6 | AAA domain-containing protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
A0A1Y2D5P2 | A0A1Y2DEH9 | A0A1Y2D5P2 | A0A1Y2DEH9 | AAA domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A1Y2D5P2 | A0A1Y2ENK7 | A0A1Y2D5P2 | A0A1Y2ENK7 | AAA domain-containing protein. | Zf-primase domain-containing protein. | 0.989 |
A0A1Y2D5P2 | A0A1Y2ESE9 | A0A1Y2D5P2 | A0A1Y2ESE9 | AAA domain-containing protein. | CDC45 family. | 0.943 |
A0A1Y2D5P2 | A0A1Y2EV80 | A0A1Y2D5P2 | A0A1Y2EV80 | AAA domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A1Y2D5P2 | A0A1Y2EZ18 | A0A1Y2D5P2 | A0A1Y2EZ18 | AAA domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.998 |
A0A1Y2D5P2 | A0A1Y2FQ93 | A0A1Y2D5P2 | A0A1Y2FQ93 | AAA domain-containing protein. | Origin recognition complex subunit 2-domain-containing protein. | 0.998 |
A0A1Y2D5P2 | A0A1Y2G134 | A0A1Y2D5P2 | A0A1Y2G134 | AAA domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A1Y2D5P2 | A0A1Y2G5E8 | A0A1Y2D5P2 | A0A1Y2G5E8 | AAA domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A1Y2D5P2 | MCM7 | A0A1Y2D5P2 | A0A1Y2ELY3 | AAA domain-containing protein. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |