STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2EPA5S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (290 aa)    
Predicted Functional Partners:
A0A1Y2F7H2
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.991
A0A1Y2EVZ6
S-glutathione dehydrogenase.
 
 0.944
A0A1Y2FTW3
Alcohol dehydrogenase.
 
 0.938
A0A1Y2EZ55
Uncharacterized protein.
  
 0.928
A0A1Y2FZK9
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
     
 0.843
A0A1Y2G1D7
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
     
 0.843
A0A1Y2G0B0
Thioredoxin-like [2Fe-2S] ferredoxin-domain-containing protein.
    
 0.818
A0A1Y2C5X5
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
    
  0.789
A0A1Y2DH06
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.778
A0A1Y2EXU5
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase.
  
 
 0.778
Your Current Organism:
Leucosporidium creatinivorum
NCBI taxonomy Id: 106004
Other names: CBS 8620, L. creatinivorum, Leucosporidiella creatinivora, Leucosporidiella creatinivora (Golubev) J.P. Samp., 2003, Leucosporidium creatinivorum (Golubev) V. de Garcia, M. A. Coelho, T. Maia, L. H. Rosa, A. M. Vaz, C. A. Rosa, J. P. Sampaio, P. Goncalves, M. R. van Broock andD. Libkind, 2015, Rhodotorula creatinivora, Rhodotorula creatinovora, VKM Y-2838
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.