STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FWS2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (136 aa)    
Predicted Functional Partners:
A0A1Y2FRX4
Kinase-like domain-containing protein.
   
 0.985
A0A1Y2F670
Actin family.
   
 0.972
A0A1Y2G0G3
Actin-related protein; Belongs to the actin family.
   
 0.972
A0A1Y2D9X0
Calponin homology domain-containing protein.
 
  
 
 0.957
A0A1Y2EM19
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.956
A0A1Y2DXH8
Actin family; Belongs to the actin family.
   
 0.869
A0A1Y2FFY8
Actin family; Belongs to the actin family.
   
 0.863
A0A1Y2FHV0
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.863
A0A1Y2G3A5
WD40-repeat-containing domain protein; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.858
A0A1Y2CFL0
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.821
Your Current Organism:
Leucosporidium creatinivorum
NCBI taxonomy Id: 106004
Other names: CBS 8620, L. creatinivorum, Leucosporidiella creatinivora, Leucosporidiella creatinivora (Golubev) J.P. Samp., 2003, Leucosporidium creatinivorum (Golubev) V. de Garcia, M. A. Coelho, T. Maia, L. H. Rosa, A. M. Vaz, C. A. Rosa, J. P. Sampaio, P. Goncalves, M. R. van Broock andD. Libkind, 2015, Rhodotorula creatinivora, Rhodotorula creatinovora, VKM Y-2838
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