STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2G014Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (363 aa)    
Predicted Functional Partners:
A0A1Y2DC26
Telo_bind domain-containing protein.
    
 0.973
A0A1Y2FYZ9
Uncharacterized protein.
   
 
 0.938
A0A1Y2G093
Pseudouridine synthase.
    
 0.908
A0A1Y2D4Q8
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 
 0.904
A0A1Y2ENY8
Ku domain-containing protein.
   
 
 0.865
A0A1Y2FHX2
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
    
 0.863
A0A1Y2FZJ2
SPOC like C-terminal domain-containing protein.
    
 
 0.858
A0A1Y2FXR5
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
     
 0.851
A0A1Y2DPE8
Pseudouridine synthase.
    
 0.839
A0A1Y2DX88
ATP-dependent DNA helicase; Belongs to the helicase family.
    
 0.829
Your Current Organism:
Leucosporidium creatinivorum
NCBI taxonomy Id: 106004
Other names: CBS 8620, L. creatinivorum, Leucosporidiella creatinivora, Leucosporidiella creatinivora (Golubev) J.P. Samp., 2003, Leucosporidium creatinivorum (Golubev) V. de Garcia, M. A. Coelho, T. Maia, L. H. Rosa, A. M. Vaz, C. A. Rosa, J. P. Sampaio, P. Goncalves, M. R. van Broock andD. Libkind, 2015, Rhodotorula creatinivora, Rhodotorula creatinovora, VKM Y-2838
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