STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2G447Histone H2A; Belongs to the histone H2A family. (85 aa)    
Predicted Functional Partners:
A0A1Y2ES96
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.920
A0A1Y2CY08
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.915
A0A1Y2G3U9
Histone H2B; Belongs to the histone H2B family.
 
 0.908
A0A1Y2G4C3
Histone H2B; Belongs to the histone H2B family.
 
 0.885
A0A1Y2G807
Histone H2B; Belongs to the histone H2B family.
 
 0.884
A0A1Y2FHW5
Histone H2A; Belongs to the histone H2A family.
  
0.837
A0A1Y2F4Q7
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.768
A0A1Y2DHC6
Uncharacterized protein.
    
 0.765
A0A1Y2C111
DNA-directed RNA polymerase.
    
 0.763
A0A1Y2FY94
RPB5 subunit of DNA-directed RNA polymerase.
    
  0.763
Your Current Organism:
Leucosporidium creatinivorum
NCBI taxonomy Id: 106004
Other names: CBS 8620, L. creatinivorum, Leucosporidiella creatinivora, Leucosporidiella creatinivora (Golubev) J.P. Samp., 2003, Leucosporidium creatinivorum (Golubev) V. de Garcia, M. A. Coelho, T. Maia, L. H. Rosa, A. M. Vaz, C. A. Rosa, J. P. Sampaio, P. Goncalves, M. R. van Broock andD. Libkind, 2015, Rhodotorula creatinivora, Rhodotorula creatinovora, VKM Y-2838
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.